After a decade of research and development, a major breakthrough in topical pain relief is now a reality

According to the U.S. National Institutes of Health (NIH), pain affects over 100 million Americans (nearly 1/3 of the U.S. population; more than diabetes, heart disease and cancer combined). Acute and chronic muscle and joint pain affects people of all ages, genders lifestyles and ethnic origins, so there is great demand for safer and more effective pain relief products. Yet, there has not been a major breakthrough in topical pain relief in over 50 years ...until now.

CBDMEDIC™ is the first and only family of FDA-registered topical medications formulated with FDA-approved active ingredients and infused with cannabidiol (CBD) rich hemp extract.

The CBDMEDIC™ pain-relief breakthrough is rooted in three foundational components for delivering rapid and lasting relief from joint and muscle pain: Natural Emollients, Powerful Terpenes and Endocannabinoid Modulators. CBDMEDIC™ analgesic ointments and creams were developed to provide extraordinary relief from musculoskeletal pain associated with daily living, sports injuries, arthritis, chronic medical conditions, and several other types of inflammation.

Natural Emollients

The most important objective of a topical pain relief product is to reach the muscles and joints so you can receive rapid and long-lasting relief. Most topical analgesic products use cheap, synthetic ingredients for their base, including benzyl alcohol, cetyl alcohol, diglycol stearate, glyceryl monostearate, petrolatum, etc. CBDMEDIC™’s first breakthrough was developing a proprietary method for making ointments and creams with 100% natural emollients (including organic beeswax, jojoba seed oil, cottonseed oil and shea butter) to help speed absorption of pain-relieving ingredients to the root of pain and discomfort.

Powerful Terpenes

Terpene molecules (C10H16) produce analgesic action in acute and neuropathic pain by decreasing neuronal excitability through peripheral mechanisms. Terpenes are aromatic organic hydrocarbons found in the essential oils of plants. They produce the distinct aroma associated with each plant. The therapeutic effects of terpenes are widely recognized. Menthol and Camphor are the two most widely used terpenes in topical pain management today. Other terpenes in CBDMEDIC™ products -- including Eucalyptus, Clove and Peppermint -- are combined with Menthol and/or Camphor in a proprietary process that represents another breakthrough.

Endocannabinoid Modulators

In the mid-1990s, discovery of the Endocannabinoid System enabled a major breakthrough in new therapies for reducing pain, inflammation and other ailments. The Endocannabinoid System is a group of endogenous receptors located in the mammalian brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. The endocannabinoid receptor system plays a significant role in regulating neurotransmitter function. One receptor that is being actively studied is called CB1. It is found in spinal and peripheral nervous tissue (including areas important for pain perception).

Although research into modulation of the endocannabinoid system is still in its early phases, studies published in the British Journal of Pharmacology and elsewhere have reported that some terpenes have been identified as an allosteric modulator capable of slowing down neurotransmitter signaling. These findings help us understand the potential therapeutic benefits that certain terpenes may have with pain perception and how they can support faster reductions of pain.